- pregnancy and lactation
- infection of the upper respiratory tract
- unregulated thyroid disease
- advanced diabetes
- heart disease
- blood diseases (haemophilia)
- cancer – during treatment only
- infection with HIV or Hepatitis
- scar and keloid formation
- kidney disease
- skin disease (albinism, psoriasis)
- inflammation of the conjunctiva and the eye
- taking steroids, antibiotics, anticoagulants, retinoids
- Drugs and drugs that thin the blood
- Immunosuppressants